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Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

在此新年之际,我同夫人向你及你的家人致以节日的问候,并祝你们新年快乐、事业有成、家庭幸福。
2013年,勇士队曾在中国与洛杉矶湖人队打过季前赛,而森林狼队则是首次来华。

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

Her mother Stephanie Boyden, 32, says Bobbi is a 'diva' who runs to the stage when her name is called - and screams when she has to leave.
周边环境:这栋房屋坐落在摩德纳岛(Modena Island),距萨凡纳市中心大约20英里(约32公里)。据该房源的代理人说,该社区设有门禁,在栎树丛与咸水湿地之间坐落着大约20栋房屋。摩德纳岛是斯基达韦岛(Skidaway Island)的一部分,岛上有一座由佐治亚大学的海洋学研究所和一座大型州立公园。

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

EMPIRE (Fox, Wednesday) The filmmaker Lee Daniels (“Precious,” “Lee Daniels’ The Butler”) is behind this new hip-hop soap opera starring Terrence Howard as a rap mogul with a terminal disease.

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

Goldman Sachs will pay out big bonuses, be publicly vilified for a month and then go quietly back to printing profits.

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

v. 擦亮,磨
adj. 年长的,高级的,资深的,地位较高的
Master of None
We will strive to boost employment and business startups.

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
From the themed collection: 陶瓷企业与供应商的“智斗”内幕
Perspective

Trends and targets in antiviral phototherapy

智能烤箱
Gitanjali因为拿下了本次最高奖项,从而获得了一笔2.5万美元的奖金。
2.管理自己,对他人负责
这种增长为中国电影业未来的发展奠定了坚实的基础。

Graphical abstract: Trends and targets in antiviral phototherapy
From the themed collection: 智能卫浴已成家装行业的主流
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

I once had an advisor that said to me when I expressed fear of a difficult class, "Do you want to get an education or not?"

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

2005年初,斯通和其联合创始人爱丽莎卡玛赫特和朱瑞德斯贾丁斯发现,使用博客的女性规模庞大,但主流媒体却很少会引用她们的文章。于是,三人决定召开一次草根会议,并吸引了谷歌和雅虎(Yahoo)等赞助商。门票很快销售一空,不久,她们便成立了BlogHer.com。这个博客发布平台把撰写博客变成了许多女性可以用来赚钱的一项业务——2009年至2012年期间,这家公司向5,000名博主支付了超过2,500万美元。目前,这个平台的用户已经超过9,200万人。

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

妮妮·切利(Neneh Cherry),《空白计划》(Blank Project), Smalltown Supersound
13 Reasons Why

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

你可以在AskMen.com网站上看到完整榜单。以下是最性感女人前十名:
5. Starbucks. Brand love: 26% / Social Business Index Rank: 26

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
From the themed collection: 深圳:短租公寓1天 骗取3月租金
Open Access Review Article

Diagnostic technologies for COVID-19: a review

这一新数据公布之际,杜特尔特正抵御国内外对其禁毒运动的指责,已有60万名潜在嫌疑人向当局自首。
健全激励机制和容错纠错机制,给干事者鼓劲,为担当者撑腰。广大干部要主动作为、动真碰硬,与人民群众同心协力,以实干推动发展,以实干赢得未来。

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

4.British people may seem to apologise a lot, but it doesn't quite mean the same thing here. In the UK, "I'm sorry" actually means either a) I didn't hear you; b) I didn't understand you; or c) I both heard and understood you, and I think you're an idiot.
2Canada
正是由于零部件的不断缩小,这些科技设备的运算效率才得以释放,让它火遍全球。
Purchase products like magazine racks, shelves, and desk organizers that will keep your supplies and resources in order and close-at-hand. We love the File File, $24.95, at CB2.com (pictured above).

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

Ms Rogers added that she had not given her son parental consent to play the game as stated in its terms and conditions, and that as the game was free to play, the studio could not claim loss of profit as a result of the cheats.

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

36岁的阿德里亚娜·利马排在第四位,其收入为1050万美元,初为人母的罗西·亨廷顿-怀特利(950万美元)与25岁的卡莉·克劳斯(900万美元)分别位列榜单的第六位和第七位。
“这是一个目标,也是我们想经历的事情”,库里赛后表示。“这将会是一个巨大的成就,因为做一些在联盟历史上还从未发生过的事情,感觉会是非常与众不同的。你永远也不会知道,这种机会是否还会再次来过。在取得这一连串的胜利过程当中,有许多许多的不可掌控的因素,特别是在赛季的开局阶段。”

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

……睡着了。

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

5. The 2012 Ig Nobel Chemistry Prize

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

exposed
The number of moviegoers in 2016 reached 1.37 billion, an increase of nearly 8.9 percent year-on-year.
挖掘者认为这个墓地可追溯到1700年前,在当时的中国,库车在控制西部前线(西域)上扮演着关键的角色。由于丝绸之路的路线有经过西域,所以控制这个关键的区域对中国统治者来说是非常重要的。
Dachis says: Adidas added more than 34 million new fans and followers in just 12 months this year. The company put that audience to good use and benefited from high levels of positive discussion all year long.

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
From the themed collection: 去年全国300城土地收入破4万亿
Review Article

Influenza neuraminidase: A druggable target for natural products

美国在2014年的新增工作岗位被设定为300万个—这是自1999年以来最大的增加量。新增工作岗位的增加预计在2015年将会对得到持续,这将确保消费者支出得到持续的动力;同时汽油价格的下降也将为家庭支出节省额外的开支用以购买其他的商品和服务。详见:汽油价格在2014年下降美国将会节省140亿美元开支。
“为什么这件事发生在我女儿身上?”她说,“因为枪支造成的死亡太多了,我不知道还要死多少人。”
Facebook CEO Mark Zuckerberg
《嗨翻姐妹行》
沃克排名第六,得益于他演艺生涯中最卖座的影片《速度与激情6》。在因车祸悲剧丧生之前,他已经完成了《速度与激情7》的大部分拍摄工作。据称环球影业(Universal)不会重新拍摄该片,而会对后续拍摄作出相应调整。

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
From the themed collection: 7月起公积金缴存基数调整
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

3. oDesk&Elance
Neighborhoods

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

Sonneborn says he's been dismayed not only by what he sees as Trump's troubling decisions and juvenile moments but also by the president's response after a counterprotester was killed during the August white nationalist rally in Charlottesville, Virginia — which is what cemented Sonneborn's decision to seek office.

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

['steitm?nt]

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

总排名76位的新加坡管理大学(Singapore Management University)李光前商学院(Lee Kong Chian School of Business)是首家进入这一排行榜的新加坡商学院。今年共7家亚洲商学院上榜。李光前商学院校友在亚洲商学院中最具国际流动性。他们在流动性指标方面排名第25,比在亚洲商学院中流动性排第二的台湾国立中山大学(National Sun Yat-Sen University)高57位。
互联网已经让世界变成了平面,Facebook让我们大家团结起来,组成一个大家庭。我们的祖父那一辈人是地区的传承者,我们这代人是国家的传承者,而你们则是世界的传承者。你现在和任何人的联系只有4.74个人的距离,到达全球任何有人居住的角落平均只需要两天时间。你可以踏上旅途。无论是非洲、欧洲、印度、中国还是巴西,前往那些能让你学到最多东西的地方,拥抱那个可以教给你最多东西的国度。
Siddeeq现在已经是一位退休教师居住在中西部城市Indianapolis,他表示当大学联系到他的时候他震惊了。
docu[=doc教]+ment→用来教的东西→文件;证书

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

这句简练、言之有物、几乎可称之为妙语的话提醒我们,即便接下来的奖项都相当雷人,还是有人能够做到直白的。
提问
库克决定通过增加派息和回购股票扩大其现金返还计划,帮助缓和了与维权投资者的关系。目前它总共向股东返还现金940亿美元。最终,库克以足够的坚忍抵挡住挑战,迎来了iPhone又一波增长捷报,以及从乔纳森?艾夫爵士(Sir Jonathan Ive)的设计室诞生的新产品。
It was not an auspicious start to the new year for bitcoin investors.

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

4. Add Color
n. 好客,殷勤,酒店管理

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

Format: After a one-week orientation, classes are held on alternating weekends on Fridays and Saturdays, with accommodations provided on Friday nights. Final term sessions are held on campus for two weeks with the remainder of the term completed online.
Lawrence, 26, took the top spot largely through a slice of the profits from the final movie in the Hunger Games franchise, as well as a big upfront fee for her forthcoming space adventure movie Passengers, Forbes said.
Teach First在2002年创立之初的目标是鼓励更多的毕业生尝试教学。由于担心该国最优秀的人才都被吸引至伦敦金融城、会计和法律行业,它希望为公立学校培养一些人才,以解决教育不平等问题。
来自用卫星采集的独立温度测量结果没有显示2014年是记录年,但是接近记录。几位科学家说,卫星测量的数据反映的是大气层的温度,而不是地球的表面温度,所以卫星数据会与来自地面和海洋表面的测量结果略有不同,并不奇怪,而表面的温度测量显示了创记录的温暖。
据第三方市场情报公司IDC日前公布的数据显示,去年中国智能手机制造商华为、OPPO以及vivo的年出货量大增,使得三家企业都成为了世界前5大智能手机制造商。

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
From the themed collection: 京城千余家具厂商九成面临转移
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

2014年在职高管100强课程排行榜冠军是由法国巴黎高等商学院(HEC Paris)、伦敦政治经济学院(LSE)和纽约大学斯特恩商学院(Stern School of Business at New York University)三家合办的Trium课程。排行榜前5位继续由洲际EMBA课程把持。
1.和平年代
Seychelles

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
From the themed collection: 家居市场景气指数现三连涨
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

Indeed, last year produced the usual crop of new euphemisms for firing people. Infosys announced an “orderly ramp-down of about 3,000 persons”. Upworthy, a small media company, had the nerve to call sacking 14 people an “investment lay-off”. Otherwise, 2016 proved that the most egregious jargon is a sign not of failure, but of overexcitement.
支持:洛杉矶影评人协会将其评为最佳影片。

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

小女孩名叫Neshama Spielman,来自耶路撒冷。她是4年前在“圣殿山筛选项目”中发现这个护符的。该项目旨在检查从神圣犹太教遗址移来,未经考古检测过的泥土。当年,Spielman只有8岁。
祝节日幸福如意。
According to the index, tourists are "spending overwhelmingly" to shop -- and not to dine -- in the top 20 destinations outside of Europe, despite many of them being world-famous cuisine capitals.

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

Xinhua reported in 2015 that the MOE and five other central government departments were putting together a task force to ensure that football thrives in the country's schools.
周二在上海举办的中国国际机器人产业发展高峰论坛称,2017年,工业机器人的销量和增速均创新高。在这些工业机器人当中,有37825台为国产制造,同比增长29.8%。
Entrepreneur Pat Crowley, the hydrologist who invented the Chapul cricket protein bar, used Bigcommerce to validate early interest in his products and build the momentum to negotiate deals with health food stores and supermarkets. The team recently recommitted toBigcommerce, despite a compelling opportunity to switch to the Shopify platform for far less money. “We don’t think we will outgrow them anytime soon,” he said.

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

com共同,miss=mit送-共同送东西到指定处-委托com共同,mission(n 使命,任务)-受了别人的委托,说明你得到了别人的信任,所以这是一种使命。

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

2.The Fresh Prince of Bel Air was Almost Bankrupt

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

Five programmes feature in the pre-experience ranking for the first time. The highest new entrant is Lee Kong Chian School of Business at Singapore Management University. The school came second in terms of the international mobility of its graduates, and is the first school to feature in both pre-experience and post-experience rankings.
立场:拒绝在感恩节开门营业

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

While British schools moved up two places on average, French schools, the largest group from any one country, fell one place on average. EMLyon Business School dropped outside the MBA ranking and lost 15 places overall, while Edhec Business School failed to make it into the Executive MBA ranking and lost eight places overall as a result.
变化世界中的得与失
"这是自然保护的一次伟大创举。"
据此网站统计,排名第二的慈善明星是前迪斯尼明星后转型歌手的麦莉塞勒斯。准爸爸查宁塔图姆名列第三。

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
From the themed collection: “双11”家居卖场就该抵制天猫
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

Lisa Stone
perspective

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
From the themed collection: 2019年起,你的社保将有大变化!
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

Quite a few students were disillusioned by UK visa regulations. “A lot of people saw the programme as a gateway to employment in Europe,” says one. “If this was the objective, then a lot of them would have gone away unfulfilled.”
居民消费价格上涨2%;

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
From the themed collection: 遭遇连亏 皇朝家私转型定制+电商
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

政府将于本周五发布新的就业市场报告,此次的报告将因飓风“桑迪”而出现失真。10月下旬的飓风给东北地区造成严重破坏,使很多人失业。经济学家说,“桑迪”有可能导致11月官方就业岗位总数暂时减少10万到15万个,这样一来,就业增量就不足10万,甚至还要低很多。[qh]

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

You are supposed to enjoy life, not be stressed out all the time. If you spend most of your days stressed about everything that going on at work, you are not at the right job.
Now, Curry and the Golden State Warriors are right road of adding another accomplishment.
Ten years ago, Steele was a successful investment advisor speaking at ITU World, a United Nations conference on technology for government. That same week, California experienced its first-ever gubernatorial election recall. Steele couldn't believe these kinds of hiccups were happening during such important races (the infamous Florida presidential election recall was only three years prior), so she decided to solve the problem herself. To date,169 countries, including Bosnia-Herzegovina, used Everyone Counts' electronic voting platform, as did the Academy Awards committee.
['elig?nt]

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

“We sell cars+ , if you don’t give us cars, naturally we won’t be able to go on, we’ll close,” Wang said in an interview, estimating import dealers are losing between 3 million and 10 million yuan a year each. The group seeking compensation represents 30 of the roughly 40 remaining imported Hyundai dealers in the country.
[m?:'t?liti]

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

4.你的同事会泄密。
May you have the best New Year ever.
“这是关于‘我们是谁’的基本问题,”伦敦大学伯克贝克学院的政治学教授埃里克?考夫曼(Eric Kaufmann)说,“作为这个国家的一员意味着什么?它是否已经不再是‘我们’的国家?——‘我们’是指占多数的民族。

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
From the themed collection: 北京限房价项目开闸迎“大考”
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

n. 董事,经理,主管,指导者,导演
Since its first release in 1995, many new versions and sequels have been created. However, fans say none could replace the breath-taking and tragic tale of the original.
The second chart shows the real federal funds rate (ie discounting for inflation) and the real natural rate. Again, when the federal funds rate is above its natural rate, EM crises are more common.

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

抓好金融体制改革。
An international medical journal's retraction of 107 research papers from China, many of them by clinical doctors, has reignited concerns over academic credibility in the country.

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

如果答案是“是”,那么也许你是D型人格的人。
Tencent, with an estimated value of $44.7 billion, was crowned this year's Most Valuable Chinese brand on a list released by the Hurun Institute on Thursday, marking the second time in a row it came up on top.
The fruit is placed into the mold when it's young and undeveloped.

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

奥巴马赢得了第二场辩论挽回颓势。虽然他也赢得了第三场,外交政策并不是选民关注的主要问题,这不大可能导致较大的选票波动。
达奇斯说:年底iphone5和迷你ipad的发布,消除了海内外制造业和乔布斯死后遗留影响的争议,这使得苹果成为年度最大的赢家。

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

TV Movie: “Sherlock: The Abominable Bride (Masterpiece)” (PBS)
The U.S. Veterans Day holiday also coincides with other World War One-era holidays around the world, including Remembrance Day in Britain and the Commonwealth nations of Australia and Canada.
Her mother Stephanie Boyden, 32, says Bobbi is a 'diva' who runs to the stage when her name is called - and screams when she has to leave.

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

男性使用这个密码的几率是女性的2.8倍。

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

吉尔伯特表示,对可穿戴设备的不断试验十分重要,但是现在短期内,人们还需要探讨一下:“技术的演进以及企业的研发力量共同推动了现有可穿戴产品的发展,但它们是否真的能够满足用户的需求;各公司又是否需要探索不同的合作模式,让可穿戴设备不仅限于早期使用者的圈子,而是被主流人群所接受”。
供给侧结构性改革:去产能、去库存、去杠杆、降成本、补短板

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
From the themed collection: 美克家居联手苹果做智慧家居
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

虽然与其他四部电视剧相比,《大唐荣耀》的评分并不算低,但是仍然有许多观众给出了差评。
加一些颜色。丰富的颜色可以让你充满活力。如果可以的话,可以选择一些色彩鲜艳的桌子和椅子。

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
From the themed collection: 楼市去库存不搞“一刀切”
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

Framing the ’80s
3.现役军人

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

“有些诡异的是,这跟马克o贝尼奥夫创立Salesforce.com时的情形非常相似,这点地方根本不够从事客户关系管理(CRM)使用,”米奇o哈珀表示。他与联席CEO艾迪o马查拉尼在2009年创立了这家公司。
Yu Xiuhua

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
From the themed collection: LED照明转型不易 三大挑战须重视
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

10. Copyscape

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

《小镇疑云》,BBC America,3月4日播出。大卫·田纳特(David Tennant)携第二季归来,在这部引人共鸣的英国推理剧中继续饰演亚力克·哈迪(Alec Hardy)探员(去年他在美国翻拍版的《小镇疑云》[Gracepoint]中饰演埃米特·卡弗探员)。这部剧将于周一在英国首映,制作人们已经开始谈起第二季的秘密情节了,编剧克里斯·齐布纳尔(Chris Chibnall)在接受英国杂志采访时说的话可能会让剧迷不爱听,“第二季不是讲罪案的。”奥莉薇娅·科尔曼(Olivia Colman)继续饰演艾丽·米勒(Ellie Miller)探员,夏洛特·兰普林(Charlotte Rampling)和玛丽安娜·琼-巴普迪斯特(Marianne Jean-Baptiste)也加入了演员阵容。
在过去的12个月里,这位22岁的T台女王兼真人秀明星赚得2200万美元,首次登顶福布斯模特收入榜。
Ellen is a stand-up comedian and is best known for her self titled talk show, which she's hosted since 2003.
伊纳里图表示:“我差点忘记感谢所有参与拍摄的美国印第安人了,没有他们,这部电影不可能拍摄出来。我能够和这些人一起活着拍完这部电影,心中的惊喜和骄傲难以用语言表达。”

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

榜单前十名中的其它外国影片为《变形金刚5:最后的骑士》、《摔跤吧!爸爸》、《加勒比海盗5:死无对证》和《金刚:骷髅岛》。

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

‘Unfortunately, while the newest episode may be a fantastic addition to the Star Wars franchise, ‘starwars’ is a dangerous password to use,’ said Morgan Slain, CEO of SplashData, Inc.
“‘降温’措施(是)影响香港(住宅)地产市场的最重要问题,”莱坊估价主管林浩文(Thomas Lam)说,“这正是过去两三年里所有大型机构的方案都在关注写字楼市场的原因。”
May its blessings lead into a wonderful year for you and all whom you hold dear.祝福你及你所爱的人新的一年中万事如意。

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

通常在垃圾桶里东西是没有价值的,不需要任何检查,但Qube试图用“世界上第一个智能垃圾桶”来改变这一现状。Qube声称可以帮助你监控你的垃圾,帮助你利用创新技术回收垃圾。
众所周知,蝙蝠侠的扮演者不再是克里斯汀·贝尔,而是肉肉的本·阿弗莱克。他将打败超人,拯救哥谭镇。

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

今年年底标普500(S&P 500)指数会在2650点上方吗?
[?'fektid]

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

In 2013, the total number of applicants who qualified for the national service exam reached a record 1.52 million. In 2014, the total number decreased for the first time in four years to 1.41 million, the People's Daily website said.

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

vi. 过活,进展,进食
他说,薪酬是个问题(2010年记者的年薪中值为3.6万美元)。他不知道自己能否靠做记者的薪水供养家庭并送孩子上大学。而且还有一点没错,记者的压力和工作时间可能会令人感到精疲力竭。但他说,我不确定自己换个工作是否会开心,也想不出任何一个工作会像做记者这样让我觉得兴奋或有成就感。
其实我一直都在等你提到篮网队的处境,既然你没说,那就我来说吧。林书豪已经因腿筋受伤缺阵几周了。他们是唯一有摆烂权利但是不摆烂的球队!

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

Murietta belonged to a gang known as the Five Joaquins, who were notorious bandits during the height of the California Gold Rush. While Murietta's criminal activity likely did not have any political undertones, he nonetheless became a symbol of Mexican resistance as American settlers ventured to California. Unfortunately for him, this pushed the government to put a bounty on his head, leading to his murder and beheading. Luckily, Banderas's character didn't fall to the same fate.
The reality turned out to be tougher than he imagined. “I saw it as a two-year opportunity,” says Mr Ravenscroft. “The grinding reality is that it’s a slog.” Moreover, his mentor worked at Lehman Brothers, the bank that collapsed in 2008. “It wasn’t quite as long a mentoring relationship as I’d hoped,” he laughs.
单词polish 联想记忆:
Agents and investment institutions are now flooding the sector, causing additional changes to content and platforms in the world's second-largest economy, the report said. A number of Internet gurus, including Lei Jun, investor and founder of tech firm Xiaomi, Zhou Hongyi, CEO of Qihoo 360 Technology, and China's richest man Wang Jianlin have all directly supported live video-streaming websites, a strong indication of the growing interest from capital investment.

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

当她的妈妈来到学校整理她的遗体时,其他的同学把自己的名字和电话号码给了这个悲伤的女人,要求她联系自己的父母,让他们脱离这个网瘾训练营。网瘾训练营其中一种实践方法就是限制学生与外界接触。它是通过基于恐惧的培训方式和严苟的纪律来“纠正”学生行为的。
deprivation

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

他告诉《中国日报》:“中国医生每天要看多少病人?可能超过50个。我们怎么可能有时间和精力做研究或发论文呢?”
3. 丹·韦斯(Dan Weiss),《14》,Pi Recordings。《14》的内容如此丰富,整张专辑的作曲由鼓手丹·韦斯一手包办:细节丰富的室内乐,前卫的啸叫,新音乐无词人声与北印度音乐。相比这个宏大的音乐参照系,更令人印象深刻的是,韦斯集结了12名同行乐手,把所有音乐元素融汇为流畅的整体。
《三生三世十里桃花》的豆瓣评分为6.4分,一些网友认为,这部剧的爱情戏码太多了。

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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泰勒·斯威夫特vs. 凯蒂·佩里
今年2月的时候,玛蒂参加了J.Mendel2015秋冬高级成衣发布秀(图)

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