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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

proper拥有+ty→财产;所有物;特性
罗宾哈丁(Robin Harding)

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

4) I often feel inhibited in social interactions 0 1 2 3 4
Sliced into eight pieces, the pizza works out to $250 per slice, meaning it costs roughly $50 per bite.

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

From the themed collection: 楼市调控须“查缺补漏”
Open Access Perspective

Soft matter science and the COVID-19 pandemic

9.千万别相信民调

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

这部13个小时的,关于长毛狗经历的影片花了45年才来到美国的影院,但时机却恰到好处。里维特先生淘气地在巴黎、法国文学与若干永恒的哲学谜题(真实的本质是什么,我们怎么知道我们知道,因与果之间的联系)之间徜徉,它既是一个迷人的,被重新发觉饿出来的艺术品,片长简直疯狂;与此同时,也警示着电影的未来。一切都已经做过了,一切都仍然是可能的。

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

“在这种情况下,这些学生的言论自由权利根本没有被侵犯。”
Colliding Neutron Stars
It also said 98 percent of government-sponsored students returned to China. Government-sponsored students who study abroad have chosen to pursue disciplines most needed in China, including engineering, the pure sciences, agriculture and medical science.
美与进化

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
From the themed collection: 甲醛影响租客对长租公寓的信任
Perspective

Trends and targets in antiviral phototherapy

公司:儿童用品公司BooginHead
While Cousins' volatile personality and high-usage tendencies present challenges, there are numerous justifications for rolling the dice:
11. 另外26部我喜爱的影片——为什么不呢?其中很多影片本可以跻身我的十佳之列的。《迷失1971》(’71)、《艾米》(Amy)、《失常》(Anomalisa)、《骇客交锋》(Blackhat)、《芝拉克》(Chi-Raq)、《机械姬》(Ex Machina)、《实验者》(Experimenter)、《诉讼》(Gett: The Trial of Viviane Amsalem)、《恐龙当家》(The Good Dinosaur)、《伟人》(The Great Man)、《头脑特工队》(Inside Out)、《奋斗的乔伊》(Joy)、《洛杉矶消逝的风景》(Lost Landscapes of Los Angeles)、《魔力麦克2》(Magic Mike XXL)、《办公室》(Office)、《结果》(Results)、《荒野猎人》(The Revenant)、《西默简介》(Seymour: An Introduction)、《小羊肖恩》(Shaun the Sheep Movie)、《女间谍》(Spy)、《冲出康普顿》(Straight Outta Compton)、《橘色》(Tangerine)、《廷巴克图》(Timbuktu)、《生活残骸》(Trainwreck)、《白色上帝》(White God)及《狼群》(The Wolfpack)。
老虎要猎食,鸟儿要飞翔;

Graphical abstract: Trends and targets in antiviral phototherapy
From the themed collection: 雄安新区规划编制体系的创新实践
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

Sari Davidson

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

[di't?:min]

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

Sales of previously owned homes have slipped every month since July, according to the National Association of Realtors. That coincides with the surge in borrowing costs across the economy as a result of the Fed's signals about its bond-buying program.
My arms are wide open for you this New Year.我张开双臂,盼与你共度新春佳节。

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

The truth is, to shut our door to the outside world would not help China do its own things well, so China will continue to open to the outside world, with this opening-up being a gradual process.
14. 《与外婆同行》(Grandma),导演:保罗·韦兹(Paul Weitz)。

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

This research involves a large longitudinal study of emotion in interactions within married couples.
《三块广告牌》是一部黑色喜剧电影,由奥斯卡得主马丁?麦克唐纳执导。

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

中国房地产公司一直在加大促销力度和降价,以保持销量。
She suffered anorexia while in an abusive relationship after she arrived in Los Angeles.
New residential property prices in China grew faster in October despite a slew of restrictions on purchases,
My arms are wide open for you this New Year.我张开双臂,盼与你共度新春佳节。

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

Industry Kitchen是位于纽约市南街海港的一间餐厅,你可以在这里购买到这款24K黄金比萨,其售价高达2000美元。顾名思义,黄金披萨因为覆盖了24k黄金金片而闻名。

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

这颗梨形蓝钻被命名为“蓝色”,重13.22克拉,拍前估价为2100万至2500万美元。
愿女儿的新年祝福带给你快乐。

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

自迈克尔?哈内克之后,再没有人像希腊导演欧格斯?兰斯莫斯那样喜欢在电影作品中解剖社会习俗了。两年前,他的电影《龙虾》用其看待社会的辛辣视角完全征服了戛纳电影节。在《龙虾》描述的社会中,如果成年人无法在45天内寻找到一个爱侣,就会变成动物——这也是我们的世界,只是将集体思维和从众性推向了最大的极限。如今他又带着新作《圣鹿之死》回归,这是关于一个外科医生(科林?法瑞尔饰)和他的妻子(妮可?基德曼饰)的家庭惊悚电影。这位妻子也是一个医生,她像朋友一样对待没有父亲的少年马丁。马丁似乎决心暴露这个家庭的秘密,并揭开这对夫妻过去的一段可怕的创伤。这部电影想表达的难道是家庭(也有可能是社会)的平静有时候依赖于共享商定的谎言?不管是不是,准备好接受惊吓吧。该片将于11月9日在丹麦上映,11月16日在俄罗斯上映,11月30在中国香港上映。(A24制片公司)

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
From the themed collection: 中东LED照明灯具市场蓬勃发展
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

The gold market may be obsessed about the dollar and prospect of a rise in US interest rates. But there’s another factor looming on the horizon: a fall in gold mine supply.

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

During the RoboCup 2500 contestants from 40 countries competed in 15 competitions with various types of computerized soccer robots, healthcare robots, rescue robots and dance robots.
We learned that animals may make choices based on aesthetics.
6. You don’t just pass in front of the TV if i’m watching football, you better crawl on the floor.
What Mr Ravenscroft liked about it when he was choosing his graduate career path was that it of-fered the best of two worlds. He would be fast-tracked into the classroom, earning a salary, being mentored by an executive from the private sector and making contacts with business; in return, he would commit to teaching for two years and complete a teacher training qualification.

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

安娜还补充道,在巴西筹办世界杯期间,巴西人民却在遭罪。由于大型建设项目造成交通拥挤,耽误了居住在城市郊区穷人的上下班时间,她认为只有富人才会在世界杯倍感享受。
专家表示,2016年对中国电影业来说是非凡的一年,因为它实现增长的同时面临着多种挑战,包括互联网的快速发展、中国观众日益高雅的品味和国家的经济衰退。
2016年的年度色彩与以往不同,它是两种颜色的组合:粉水晶(Rose Quartz,一种矿物粉色)和宁静蓝天(Serenity,一种淡蓝色)。在该公司的网站上,这两种颜色浑然融为一体,看不清它们的界线。
But pop's wider world also offered a lot of pleasures from artists all over the spectrum, such as the 20th century legends like Blondie and Tori Amos, and upstarts like Dua Lipa and Girl Ray.
12岁的年纪,大多数的小女孩都还在向父母争取打耳洞的机会,努力适应高中生活,从青少年时代开始为将来做准备。

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

200911/88512.shtmlA love letter to a US college student from the girlfriend who was to become his wife is finally on its way to him - 53 years after it was written in 1958.
“…was asked ttell the interviewer a little about herself, and didn’t have anything tsay.”

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

特朗普说道:"她唯一能做的就是打女人牌。我愿意看到美国能有一位女主席,但希拉里绝对是错误人选,她简直就是一场灾难。"

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

如何重置iPod

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

你花在上网上的时间多于你工作的时间
信任感依然会是商业领域中唯一且最关键的问题。
Premiered in August, the 48-episode TV series is a fictional story, with a plot centering on struggles and romance during the Qin Dynasty (221-206 BC).
Rio - home to the 2016 Olympics and a host city for the 2014 football World Cup - beat Greece as the most searched-for destination.

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

It has to take over most of every waking minute. It's all you want to talk about. Prepare to watch people's eyes glaze over.
埃尔多安在国内也受益于与吕特的争执,他寻求将外交争端扩大至针对所有欧盟国家,尤其是德国,后者同样因土耳其在德国的大型土耳其社区拉票而与安卡拉发生争执。
日立数据系统:提升士气的狗狗节
Seoul insists the activists have a democratic right to send the leaflets, but has appealed for restraint to avoid overly provoking the North.

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
From the themed collection: 建筑材料板块市场需求放大
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

中国政府鼓励向中小规模的借款人放贷,其中很多贷款者没有信用纪录。分析师预计,在金融上表现活跃但没有信贷渠道的中国消费者有5亿之多。
单词benefit 联想记忆:

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

Yes. Mr Modi’s overnight ban on using high-value bank notes was a big shock, and seriously disrupted the economy. But it delivered rich political rewards, bolstering the premier’s image as a decisive leader willing to take tough action against corruption. With the next general elections due in 2019, Mr Modi will be tempted to deliver one more big bang to dazzle voters. Watch out for dramatic action against wealthy individuals holding properties in others’ names to hide their ownership.
伯利兹城最富盛名的旅游胜地莫过于巨大的水下天坑--蓝色巨洞以及玛雅遗址。
乔布斯在苹果博览会上手持iPhone ,2007年,1月9日,旧金山
经济大萧条在全美各地产生了破坏性的影响,然而很少有地区像亚利桑那州那样遭受重创。20世纪初,该州借助强大的旅游业和房地产市场蓬勃发展。住房中位数价格在2003年到2006年间上涨了70%——仅次于内华达州的增幅——带动了更多的房屋和建筑行业工作岗位。直到2007年接近年底的时候,亚利桑那州的月失业率都一直维持在3.5%的低水平。但是随后经济陷入低谷。住房价格从相比高点惨遭腰斩,亚利桑那州6%的房产在2009年收到了止赎通知。在2009年和2010年的大部分时间里,该州的失业率保持在两位数居高不下,从最近五年的失业率情况看,恶劣程度仅次于内华达州。2008年以来,该州的家庭收入以全美最快的速度下降。
The Education Ministry has also taken some measures, such as canceling testing results and noting cheating in personal records.

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
From the themed collection: 标准是智能家居普及的最大阻碍
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

Having longer does not seem to make it easier, however. Proper time management is essential in order to maintain the momentum. “A couple of obligatory projects would help keep the pace and avoid a very intense last quarter,” commented one graduate from Warwick Business School. Overall, the graduates from the class of 2012 took slightly longer than 2.5 years to graduate.
Ujiri's well-timed and thoughtful moves should help reverse the Raptors' backsliding.
WASHINGTON (MarketWatch) — The U.S. economy finally got a big jolt of energy in 2014 after the lamest recovery since World War II. And 2015 is shaping up to be an even better year.

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

The result doesn't look much like a nose—it's a bottle filled with liquid nutrient that cultivates bacteria. But give the “nose” a blood sample and let it sniff for a few days, and the bottle's dots will change color to indicate what bacteria, if any, it identifies.
Some 695 million netizens used mobile phones to access the Internet in 2016, with a growth rate exceeding 10 percent for the third straight year, the report said. Smartphone-based Internet use accounted for 95.1 percent of all Internet users, up from 90.1 percent in 2015.

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
From the themed collection: 榕城家居建材业寡头格局初现
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

该机构还表示,周二仍有876个岗位无人报名,其中包括上海和西安的铁路警察。
此外,该报告还指出,雨果博斯、雪佛兰和舒洁则跌出了该榜单。
The drama got 7.2 points on Douban, receiving criticism for having too much romance and too few of Zhou's struggles.

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

adj. 优雅的,精美的,俊美的
The survey discusses projections for going forward: "The cost of living is always changing and there are already indications of further changes that are set to take place during the coming year."
Hartz started Eventbrite, an online ticketing platform, with her now-husband Kevin in 2006. Since its founding, the company has raised $140 million from firms like Sequoia Capital and Tiger Global Management and reached $2 billion in gross ticket sales this September. Entrepreneurship forced Hartz to appreciate candid and collaborative conversations. "I had to learn how to ask for help," she says. "Everyone always thinks it's brave to go out alone, but I think it's even braver to put yourself out there in front of others, and to figure out how to work together."

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

No, this doesn't mean you should abandon your LinkedIn profile for fear of a suspicious boss. But it does mean you should be more careful. For one, turn off your activity broadcasts so that every savvy move you make isn't announced to your entire network. Here's how: From the homepage, hover over your photo in the top right corner, and click on "Privacy & Settings." From this page, click "Turn on/off your activity broadcasts."

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

A moment of panic followed, before the teenager decided to take matters into his own hands and find a way out.

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

科学家改良光合作用提高作物产量
College graduates earn more

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

At that time, the chief executive was also under pressure, given Apple’s lack of clear product direction beyond milking the iPhone. Sensing blood, activist investors began to circle the company; first David Einhorn, then Carl Icahn, have lobbied for changes to how Apple is run and manages its finances. Mr Icahn has pushed for Apple to raise huge debt to return up to $150bn to shareholders and urged it to release more products, including a television set.
It is also argued that Friends came about as the family unity of small-town America was being replicated in major urban centers as young people migrated without the maturity or streetsmarts to live alone. Before Friends, sitcoms tended to focus on family dynamics, with parents being the central characters. But when young people strike out on their own in the big city, who do they have for support? They must rely on each other to endure through the overwhelming confusion of youth.
The central government is planning to establish a bond market connect between the mainland and Hong Kong Special Administrative Region on a trial basis this year, allowing for the first time overseas capital to access mainland bond markets from overseas. Hong Kong will be the first to benefit from such an arrangement
To start with, a year before the first iPhone was released, LG had introduced a full touchscreen phone. Even that was not the first, though. The world's first touchscreen phone was IBM's Simon, which was released in 1992. And touchscreen technology even predates the Simon. The first touchscreen device was a tablet made by E.A. Johnson in 1965 that was used by air traffic controllers until 1995. Bent Stumpe and Frank Beck made the first capacitive touchscreen in the early '70s. Unlike Johnson's tablet, it could not be pressed with the fingers. Instead, it required a stylus. In 1971, Samuel Hurst developed the first resistive touchscreen, which he called the "elograph." It responded to the fingers as well as a stylus. In 1985, HP invented the world's first touchscreen computer, called the HP-150. In 1993, Apple also released its first touchscreen device—the Newton Personal Digital Assistant. The product was a flop, recording low sales.

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

The reality turned out to be tougher than he imagined. “I saw it as a two-year opportunity,” says Mr Ravenscroft. “The grinding reality is that it’s a slog.” Moreover, his mentor worked at Lehman Brothers, the bank that collapsed in 2008. “It wasn’t quite as long a mentoring relationship as I’d hoped,” he laughs.
Mr Crabb has taken no exposure to Hong Kong’s property market since setting up in Asia 18 months ago, because he says prices are too high and affordability too low.

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

Talking to Town & Country, Industry Kitchen Executive Chef Braulio Bunay said he was inspired to create the pizza by the city's Financial District, which he described as 'the epitome of decadence'.
States are falling all over themselves to be chosen as the site for Tesla’s proposed $5 billion Gigafactoryto produce lithium ion batteries. California is competing with Nevada, Arizona, New Mexico, and Texas, and the bidding for the factory, which could employ up to 6,500 people, is said to be up to $500 million.

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

Over the next few years, large residential buildings will have to comply with Local Law 87, which requires them to audit energy usage and keep systems running at peak efficiency. Residential buildings are the city’s largest source of greenhouse gas emissions, accounting for 37 percent of the total. “The one hot-button topic is energy. How do buildings become more energy efficient?” said Dan Wurtzel, the president of FirstService Residential New York, which manages more than 500 properties. “If a third of your operating budget is related to energy and you can now reduce that cost, you can take pressure off the need for a maintenance increase.”

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

Common industries for college startups include catering, agriculture, IT, transportation, education and culture. 13.8% of the entrepreneurs were interested in hospitality and catering, while 13.7% chose agriculture, the report said.
[stres]
像中国人口这么多的国家,关于寂寞的病毒式模仿会这么流行实在是件很讽刺的事情。这句看上去很无厘头的话被用在了所有可能搭配的排列中,用在了所有场合,比如,“哥看的不是书,是寂寞。”
That's become a common refrain in Brazil - where the billions spent to build new or upgrade existing football stadiums both raised public ire about how the money was spent and has already caused ticket prices for Brazilian national soccer league matches to rise sharply. Some fans complain that's turned what were once affordable, raucous stadium experiences in Brazil into more costly and less spontaneous visits to storied stadiums like Rio's Maracana.

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

当其他同龄人每天乖乖去上学的时候,她已经出来养家糊口四年了,她不得不快速成熟起来。
During the RoboCup 2500 contestants from 40 countries competed in 15 competitions with various types of computerized soccer robots, healthcare robots, rescue robots and dance robots.

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

The country has rolled out measures to promote new-energy vehicles, including tax exemptions, subsidies for car purchases and a requirement for government departments to buy more new-energy cars.
这是中国首次占据榜单前三甲以及在前10强中占了5名。中国工商银行连续两年占据第1名的宝座,中国建设银行次之,而且中国农业银行向上移动了5名成为第3名。这三大银行与排在第9名的中国银行一起跻身前10强,中国银行是“四大国有银行”中的另一个成员。
The tightening drove some enterprises seek other financing options such as bonds or listing on the National Equities Exchange and Quotations (NEEQ).

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

stre力量,ngthen-加强力量
10.谎言和誓言的区别在于,一个是听的人当真了,一个是说的人当真了。
……被要求向面试官简单介绍自己,结果她没有什么可说的。

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
From the themed collection: 深圳中心城区道路网密度全国第一
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

If successful, the funding would underline the rapid growth of the sector this year. In April, Lufax raised $500m at a $10bn valuation.
It was visible in practically every brand that edged from the 1960s to 1970s for the season currently in stores, including Alberta Ferretti, Pucci and Etro.

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

Tuesday’s event at Apple’s new Cupertino headquarters is expected to reveal its much-anticipated 10th-anniversary iPhone, offering significant upgrades to the smartphone’s display, camera and overall design.
这部电影有趣、使人着迷,有不少迂回的、令人惊喜的桥段,让你无法预测结局。和很多好莱坞最好的电影一样,这部电影闪耀人性光辉。既契合当下,又经典隽永。
周四,央视公布了2016猴年春晚的吉祥物后,就迅速成为互联网上的热议话题。不幸的是,不少网友称被其“丑哭”。

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

The upcoming launch will mark the five-year anniversary of the sinking of a South Korean warship in 2010, with the loss of 46 sailors. The South pinned the blame on the North and effectively froze all inter-Korean trade and investment ties.
I'm only a child yet I know we are all part of a family, five billion strong, in fact, 30 million species strong and we all share the same air, water and soil -- borders and governments will never change that. 我只是一个小孩,但我知道我们都是一个大家庭的成员,超过60亿人的大家庭,以及超过三千万物种的大家庭,政府和国界永远都无法改变这个事实。

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
From the themed collection: 家居卖场开春首个“促销季”来临
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

公司:网络投票公司Everyone Counts
拯救非洲癌症患者
这部由塞巴斯蒂安.马拉比(Sebastian Mallaby)所著的《知者:格林斯潘传》(The Man Who Knew),是这项奖金额为3万英镑的奖项的第12位获奖者。该奖项奖励的是年度“最令人瞩目和愉悦的”图书。

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

C罗巨无霸般的收入主要来源于两部分。一部分是他效力于西班牙豪门皇家马德里挣得的令人眼红的3850万英镑的年薪。另一部分来源于他为耐克、豪雅表和营养品公司康宝莱代言带来的总计2200万英镑的代言费。

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

在海外工作过至少6个月的女性少于男性(比例分别为42%和52%),但动机完全一样:加强管理能力、打造自己的人脉以及提高薪资。
'Her,' which was written and directed by Spike Jonze, takes romance into the virtual realm, and its hero on a gently crazed journey of genuine passion. Joaquin Phoenix is the poignantly lonely guy who falls in love with his smartphone's new operating system. The basic conceit is a fragile one, but it's beautifully and bravely developed, as well as elegantly photographed by Hoyte Van Hoytema, with perfectly calibrated performances by Mr. Phoenix, Amy Adams and Scarlett Johansson, who is that system's voice and soul.

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

当然,它还播放音乐,也有日历,甚至给孩子提供娱乐游戏,但它也可能像别的东西一样会被黑客攻击。
明年,市长的保障性住房计划将初具规模,该计划要求在未来十年里,修建或保留20万套保障性住房。这一目标的实现取决于一项政策,它要求开发商通过修建保障性住房,来换取在市政府重新规划的社区修建更高、更密集楼盘的资格。至于政府将会如何在这项提案的雏形上添砖加瓦,开发商和保障房倡导者们都在拭目以待。

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

It is the first biography to win the prize, although Mr Greenspan’s autobiography, The Age of Turbulence, was shortlisted in 2007, the year before the financial crisis raised serious questions about the central banker’s legacy.
The annual rich list of China's movers and shakers gives a temperature check on where money is flowing in China, and underlines the growing financial muscle of the country's super-rich.

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

In terms of individual commodities, coffee prices, which are trading at about $1.62 a pound, are expected to decline significantly, with an especially bearish outlook on arabica coffee.
位于华盛顿特区的乔治敦大学(Georgetown University)麦克多诺商学院(McDonough business school)重新回到了定制课程排行榜的第15位,去年,该校因客户调查反馈率低而未上榜。只有3所学校是首次登上定制课程排行榜,包括排名第60位的伦敦卡斯商学院(Cass Business School)。

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

The registered urban unemployment rate stood at 4.02 percent at year-end 2016, the lowest level in years.

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

vt
Those concerns are casting a heavy shadow over a two-day meeting of G20 central bank governors and finance ministers due to start tomorrow. The International Monetary Fund this week already warned that it was poised to downgrade its forecast for global growth this year, saying the leading economies needed to do more to boost growth.
毕业于该项目的学员获得的金钱回报遥遥领先,毕业3年后的平均年薪为46.9万美元。
Some hits have gone so far over the top they should be winded, yet instead keep on puffing gusts of hot air, including “Downton Abbey,” “Scandal” and “Revenge.” A new addition on ABC, “How to Get Away With Murder” was a fun substitute, a lurid nighttime soap opera about lawbreaking defense lawyers — “Law & Disorder.”

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

4.闻疾病的鼻子

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

要实现有效的电子邮件营销,可不只是偶尔发一封电子文宣邮件那么简单。要想构建一套有效的电子邮件营销战略,你需要一个功能齐全的工具。MailChimp似乎是市面上最佳的此类系统,它提供了各种典雅直观的电邮广告模板、先进的分段功能和营销自动化功能。
The contiguous United States set a temperature record in 2012, a year of scorching heat waves and drought. But, mostly because of the unusual chill in the East, 2014 was only the 34th warmest year on record for the lower 48 states.
The U.S. Veterans Day holiday also coincides with other World War One-era holidays around the world, including Remembrance Day in Britain and the Commonwealth nations of Australia and Canada.

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

To start with, a year before the first iPhone was released, LG had introduced a full touchscreen phone. Even that was not the first, though. The world's first touchscreen phone was IBM's Simon, which was released in 1992. And touchscreen technology even predates the Simon. The first touchscreen device was a tablet made by E.A. Johnson in 1965 that was used by air traffic controllers until 1995. Bent Stumpe and Frank Beck made the first capacitive touchscreen in the early '70s. Unlike Johnson's tablet, it could not be pressed with the fingers. Instead, it required a stylus. In 1971, Samuel Hurst developed the first resistive touchscreen, which he called the "elograph." It responded to the fingers as well as a stylus. In 1985, HP invented the world's first touchscreen computer, called the HP-150. In 1993, Apple also released its first touchscreen device—the Newton Personal Digital Assistant. The product was a flop, recording low sales.
冷空气是被一个名为高空急流的气流循环带到美国本土的内部,这让北极的冷空气南下。但是,一个抵消这种冷空气的怪现象,让异常温暖的热带空气停留在西部地区、阿拉斯加大部分地区以及北极大部分地区的上空。

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

Good health, good luck and much happiness throughout the year.
Unfortunately, there won't be a 2014 rematch between Brazil and Uruguay, as the latter was eliminated on Saturday. If Brazil makes it to the final on July 13, the country could play Mexico, the Netherlands, Costa Rica, Greece, USA, Belgium, Argentina or Switzerland.

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

Dachis says: Adidas added more than 34 million new fans and followers in just 12 months this year. The company put that audience to good use and benefited from high levels of positive discussion all year long.

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

Beck “Say Goodbye” (Capitol)
5. Gross warns: 'Ponzi Scheme! Tipping Point! Credit Supernova!'
jewelry

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
From the themed collection: 房屋装修别让人身心俱疲
Paper

Length-scale dependence of protein hydration-shell density

7. “The Kindergarten Teacher” In his tough, weird knockout, the Israeli director Nadav Lapid spins the story of a teacher’s obsession with a child poet to create a savage portrait of fanaticism and its costs.
美国的麻省理工斯隆管理学院(MIT Sloan School of Management)位居第五,从而阻止了法国商学院囊括前五名。
201001/93725.shtml
这个由财新赞助的系列指数,是基于对民营企业的调查得出的,样本数目也比官方PMI指数少得多,往往波动性更大。相比之下,官方PMI指数则主要关注规模更大的国有企业。

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

潘通色彩研究所(Pantone Color Institute)的执行总监莱亚特丽斯·艾斯曼(Leatrice Eiseman)说:把这两种颜色组合起来反应出“一种令人慰籍的秩序感与和平感”,在这个全球动荡和缺乏安全感的时代,把这种感觉融入产品应该具有吸引力。它也暗示着,“我们”和“他们”之间没有界线。
Inga Beale出任伦敦劳埃德保险公司CEO,Mary Barra 出任通用汽车高级副总裁,这些都为2013年的女性地位写下了浓墨重彩的一笔。接下来的一年,女性地位还将继续发展,但进展会缓慢而微小,但你一定能随处看到女性的权力和影响力。再怎么说,就连日本都开始鼓励女性工作了呢。

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

n. 争斗,战斗
怎么玩扑克?
Children show “Paper-cutting Flowers” (China Southern Dance School under the China Dancers Association)

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
From the themed collection: 陶瓷行业终端渠道转型的三大趋势
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Erle Spratt, who manages M&G’s Asia property fund, an open-ended investment vehicle, says it is risky to invest directly because assets are not easy to find and price. “It is a very difficult market to buy assets in for investors like us, because developers have very substantial holdings and they tend not to sell,” he says.
时尚界通常视历史为潜在灵感的百宝囊,可供随时汲取、混合搭配。即便如此,目前这一阶段对历史的依赖也太过极端。

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