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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

succumb
艾米莉·拉塔基科斯基想(在红毯秀上)抢镜头,她选择了一件经典的舞会礼服,礼服上编织着非常别致的花纹。这位出演了《我们是你的朋友》这部影片的女演员选择了一件黑色半透明且有着精致的透空图案的礼服来展示自己举世闻名的身材。

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
From the themed collection: 智能家居产业将迎爆发期
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

The Big Tech backlash will spread to technology industry employees in 2018, as many question whether the work they do really is saving the world.
例如比利时,它的人口不到小组赛对手俄罗斯的1/10,但被认为是一个巨大的威胁。而乌拉圭尽管人口还不到400万——仅仅是大圣保罗人口的1/6——却是巴西在通往决赛之路上最不想碰到的球队之一。为何如此呢?

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

From the themed collection: 房子卖不掉 降价销售如何
Open Access Perspective

Soft matter science and the COVID-19 pandemic

The largest flawless vivid blue diamond in the world is to go on sale today at Christie's auction house.

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

Everyone on Wall Street, Main Street and Washington keeps forgetting the fundamentals of market cycles. Please remember: Investors Business Daily's Bill O'Neill, author of 'How to Make Money in Stocks, ' says market cycles average 3.75 years up, nine months down.

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

10. 2012年搞笑诺贝尔奖之医学奖
8 April
For the students interested in comparing school options around the world, US News released the fourth edition of its annual Best Global Universities rankings.
他告诉《中国日报》:“中国医生每天要看多少病人?可能超过50个。我们怎么可能有时间和精力做研究或发论文呢?”

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

继1958年瑞典世界杯之后,本届世界杯的场均进球数如狂潮般不断刷新。
玛多问道:"特鲁多承诺在上任之后,内阁中将有50%是女性。如今他兑现了承诺。那么你也会做出类似承诺吗?"
In addition to a large, educated workforce to choose from, companies are also attracted to Arizona’s pro-business regulatory climate, which ranks No. 13 in the Mercatus Center’s Freedom in the 50 States. The study cites Arizona’s right-to-work law, liability laws and eminent domain reform.
The Baltic Dry index, a measure of the trade in bulk commodities, has been touching historic lows. China, which in 2014 overtook the US as the biggest trading nation, this month reported double-digit falls in both exports and imports in January. In Brazil, which is experiencing its worst recession in more than a century, imports from China have collapsed.

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

But at the end of a madcap Golden Globes (Ms. Fey toasted it as 'the beautiful mess we hoped it would be'), the major honors soberly ended up with the favorites. David O. Russell's con-artist caper 'American Hustle' led with three awards, including best film comedy. And despite missing out in the other six categories it was nominated in, the unflinching historical drama '12 Years a Slave' concluded the night as best film drama.

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

The Thomson Reuters Top 100 global innovators program identifies innovators annually through an in-depth analysis based on a series of patent-related metrics that analyze what it means to be truly innovative.

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

[di't?:min]
在本届戛纳电影节上,女性电影制作人以及相关女性话题曾广受关注成为宣传主题。28年来,戛纳首次以女导演拍摄的电影拉开序幕,伊莎贝拉?罗西里尼(Isabella Rossellini)成为“一种关注”单元评审团主席,莎尔玛?海雅克(Salma Hayek)主持讨论会高调探讨女性角色在电影中的意义。可以讨论的话题有许多,但是真的有何改变吗?数字似乎更能说明问题,主竞赛单元的19部入围作品仅有2部来自女性导演。而后发生的“高跟鞋门”,更有.....面对外界对于影展涉嫌性别歧视的负面消息,艺术总监蒂埃里?弗雷莫(Thierry Frémaux)一点儿反应都没。他只是说,戛纳电影节的举办有着及其不公平的高标准,参展影片不能申请其他诸如威尼斯或柏林电影节。这难道是建议人们去“攻击奥斯卡”?

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

"Twenty Two" featuring the tales of 22 comfort women became the first Chinese documentary to surpass 100 million yuan at the box office.
贴近大自然。在桌上摆放一盆植物是振奋自己的一个好办法。

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

7.你要保证你不会问一些愚蠢的问题,例如:这场赛是切尔西队对英格兰队吗?
日本

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

“Airbnb is here to stay,” Mr. Gottsegen said. “Instead of fighting it, we should wrap our arms around it and make it better.”
Rank: 3
这些人造耳朵对那些遭受过耳朵伤害或者耳朵停滞发育即患有小耳畸形的人来讲是巨大的福音。
单词protection 联想记忆:

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

According to China's business magazine New Fortune's 2018 Chinese wealthy list, the top 10 tycoons' total wealth reached 1.72 trillion yuan, accounting for 18% of the combined wealth of the list's total 500, and the top 10's personal wealth has surpassed 100 billion yuan for the first time.

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
From the themed collection: 减税降费持续释放经济活力
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

This ranking measures the quality and breadth of the schools’ postgraduate programmes. It is based on their performance in the four main rankings published by the FT each year: MBA, Executive MBA, Masters in Management and Executive Education. Only schools that take part in all four rankings are eligible for a full score.
周二在华盛顿DC的乔治市附近,人们沿着被淹的波托马克河在雨中漫步。

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

n. 生存,幸存者

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

肯达尔·詹娜首次击败了15年里世界上收入最高的模特吉赛尔·邦辰。

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
From the themed collection: 东莞限价升级提醒开发商理性定价
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

If all this comes to pass, Huberty estimates that Apple's addressable smartphone market in China, which had dwindled to 10%, could triple to nearly 30%.
n. 行为,举动,品行
v. 排
Latest ECB projections predict the eurozone, which has struggled to grow as strongly as the US or UK, will grow 1.7 per cent in 2016 after hitting 1.5 per cent growth this year as QE bolsters the economy.

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

Chinese imports fell 18.8 per cent in October from the same month a year earlier, a slight improvement from the 20.4 per cent year-on-year fall in September. Sharply lower prices of oil and other commodities also helped scythe the bill.
1. Battle of the Sexes
n. 大赦,特赦
国有控股投资增速下滑1.1个百分点至20.5%,这使得国有控股投资在今年1至10月份全国固定资产投资总额中所占的比例小幅下滑至36.6%,但这仍是2011年以来的最高占比之一,反映出今年政府开支在支撑经济增长方面发挥着巨大作用。
The work suits Carlson who has been into singing and musical theater her whole life.

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

But the economic base for these capabilities is steadily declining.
债券大王比尔?格罗斯(Bill Gross)承认:“QE必须结束。”数万亿的低成本资金“扭曲了激励机制,将资产价格推高至人为水平”。但现在格罗斯说“美联储的计划可能过于仓促了”。

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

It grows naturally into the mold's shape.

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

5. 对自己的职业直觉缺乏信心

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

据国家新闻出版广电总局介绍,中国的电影票房收益在2017年上涨了13.45%,达559亿元(86亿美元),国产影片为该市场做了53.84%的贡献。
卡恩在宣布收购交易的博客文章中表示,尽管移动设备在改变我们的日常生活,但“大多数文章和网页的格式是为PC端设计,适合用鼠标点击浏览。在手机或平板电脑上浏览它们可能构成重大难题——读者希望更方便地找到对自己重要的内容。”
budget
中国富豪王健林旗下拥有AMC Theaters等产业,在今年的榜单上进入了前20位。

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

在观影从始至终,我都在问自己一个问题:这部电影到底在讲什么……这部电影的主题仿佛一锅杂烩,并不明晰。我希望制片人也在问同样的问题。
夏洛特·艾玛·艾奇逊《1号天使》
公司:The Grommet公司
企业也在其他方面受益。英国国家电网公司的业务分析经理克雷格?罗拉森(Craig Rollason)表示,他通过指导一位Teach Firste人提高了自己的指导技巧。

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

这晚,霉霉并没有参加这次颁奖典礼,虽然她提名最多。19岁的歌手Shaw表选突出,风头胜过了霉霉,在这场颁奖典礼上横扫众多奖项。
在中国北方分析出的这种病毒与1957年以前传播的病毒相似,因此,1957年以前出生的人一般都有了抵抗力,而在那年之后出生的儿童和年轻人由于没有预先的免疫力而缺乏抵抗力。1978年这种病毒在世界各地传播开来,其中包括美国。这种病主要发生在孩子们身上,因此,这次流感没被看成是真正的大流行。1977-78年的流感季节,还没有及时地生产出控制病毒的疫苗,但是,1978-79年的流感疫苗就包含了这种病毒的疫苗。

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

在英国《金融时报》的年度调查中,欧元区分析师作出了欧洲央行不会采取进一步行动的预言,尽管德拉吉试图说服市场相信:只要整个单一货币区的通胀和经济增长继续令人失望,欧洲央行就将随时准备采取行动。
“…started swearing during the interview.”
共管公寓和合作公寓一直在严令整顿,编写警告备忘录,对违规居民罚款。对于租房者来说,打破规则就可能会危及租约。共管公寓正在加强安保措施,要求门卫仔细观察来访者,同时要求居民为来访的客人签署授权表格。这类操作还引起了保险界的关注。
The Cems masters in management, the international programme provided through a network of 30 business schools, is ninth, down five places from 2015, when it was last ranked.
2. “闪光的密切:纳撒尼尔·多斯基与杰罗姆·希勒的电影”(Luminous Intimacy: The Cinema of Nathaniel Dorsky and Jerome Hiler)。赞美纽约电影节,感谢纽约电影节,举办了这样一次令人赞叹的双人回顾影展。

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

The singer/songwriter Dua Lipa has been steadily releasing a string of singles since 2015, beginning with the flirty "Be the One" and finally hitting the jackpot with "Hotter Than Hell" – both collected here on her debut album.
Season\'s greetings and sincere wishes for a bright and happy New Year!
谅解是赢家永远不会拿走一切。

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

In 2011 the owner of the tomb was identified as Liu Fei (169BC-127BC) the first king of Jiangdu an autonomous kingdom within the Han Dynasty according to China News.
Making Airbnb go away might not be so easy. A recent Quinnipiac poll found that 56 percent of the responders thought New Yorkers should be allowed to rent rooms out to strangers. “We don’t want to turn into hotels, but at the same time people want to rent out their apartments sometimes,” said Paul R. Gottsegen, the president of Halstead Management Company, which manages 250 residential properties in the city.

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

“狗屎。都在说谎,都是权宜之计,他们不过是想让自己好受些,我知道这些人都是胆小鬼,只要表面上看起来能凑合,对他们来说这就够了。”
How could we not include the ancient Chinese theory of interior aesthetics? Where your desk is situated is the most important aspect to freeing the energy in your space. Place your desk so that you face the door— the ultimate power position. Avoid placing your desk against a wall with your back facing the door, as it will interfere with the balance of your chi.
However, its alumni are the most mobile internationally, with 85 per cent of the class of 2014 having worked abroad.

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

中国国产3D奇幻/冒险片《捉妖记》2015年7月在国内上映后打破一系列票房纪录,成为2015年中国内地最卖座的电影
许多管理者提到了一些极其失礼的情况。求职者:
7. Kristen Stewart

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
From the themed collection: 人才争夺战 抢得来更要留得住
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

From the themed collection: 家居装饰展会主打色彩营销
Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

说点实在的

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
From the themed collection: 家居建材市场刮起“私人定制”风
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

Bella is the youngest model on the list, having just turned 21 last month.

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

9.忠诚待人
肠道细菌正以我们想像不到的方式干扰着我们。新的研究指出,像帕金森综合症等神经退行性疾病实际上可能始于肠道,而不是大脑。越来越多的证据显示,慢性疲劳综合征可能要归咎于人体内的微生物群系。随着肠道细菌显示出控制食欲以及改变大脑结构的迹象,而且有引起大脑损伤而导致中风的表现,我们的这个小过客(肠道细菌)有着不容忽视的力量。

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

As early as 2008, wearable technology—which can range in anything from measuring your heart rate to curating music based on your mood—has been touted as the next big moment in consumer electronics.
Recognize me?: image via blog.discoverymagazine.com
德系三巨头:由于奔驰的几款低价产品不可避免地会损害它“要么最好,要么什么都不是”(the best or nothing)的商誉,该公司也开始陷入低迷。而即将推出的新7系轿车则会进一步巩固宝马在美国富人圈中的地位。另外,起价30,795美元的奥迪A3,很可能会使奥迪的销量较2014年增长15%,新款Q7也将进一步提高奥迪的利润。
特里萨?梅(Theresa May)依然面临着党内阻力。自由民主党(Liberal Democrats)的智者兼领导人文斯?凯布尔(Vince Cable)依然认为脱欧可能不会真的发生。

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

vi. 获得奖章
源于:prim(adj 整洁的;最好的;早的)

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

It was there in Rossella Jardini’s Moschino, from the bows and bouffants of spring-summer 2009 to the Mary Quant-inspired spring 2013 collection.
不可否认,选择最老套的性别色彩似乎有点过分简化,但是潘通拥有庞大的客户群,这种选择不是为了前卫,而是为了找出平均值。

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

这就真相了,我同意。

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

美国的排放量在经过了最近几年的持续下降后,提高了2.9%。
3.3M公司
2.德语:增长了22.2%
The report also shows that despite the rising pension insurance balance since 2012, the payable number of months fell to 17.7 months last year from 19.7 months in 2012.

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

These rankings use a different methodology from the overall ranking based on academic research performance in each specific subject.
在许多情况下,这种做法已经渐渐从政界边缘进入主流。比如说,英国的执政党保守党立场是中间偏右,它曾经推进英国脱欧,公投之后,新的保守党首相特丽莎?梅(Theresa May)表现出对白人身份政治的同情。

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

Economic forecasters are counting on 2014 to be a breakout year. But whether the economy finally moves past its sluggish growth will rest on several forces playing out differently than they have since the recovery began. Some of the key questions:
Asli Erdogan, a novelist of the “dark, pessimistic,” is struggling to process her own grim experience: months in prison.
We will continue to pursue a proactive fiscal policy and a prudent monetary policy.

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

促进外贸继续回稳向好。
The big question is what oil prices will do in 2015. Oil prices are unsustainably low right now – many high-cost oil producers and oil-producing regions are currently operating in the red. That may work in the short-term, but over the medium and long-term, companies will be forced out of the market, precipitating a price rise. The big question is when they will rise, and by how much.
“网络反腐大部分靠文字、照片、视频等,从这些途径‘揪’贪官,容易流于表面化。”

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

3.Oh, yeah. That makes sense. – Because option B involves admitting that I am clueless。
《伯德小姐》

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

If successful, Hurun estimates that Mr Wang’s net worth could soar past $50bn, making him one of the world’s 10 richest men.
After months have passed without a culprit in her daughter's murder case, Mildred Hayesmakes a bold move, painting three signs leading into her town with a controversial message directed at William Willoughby, the town's revered chief of police. When his second-in-command Officer Dixon, an immature mother's boy with a penchant for violence, gets involved, the battle between Mildred and Ebbing's law enforcement is only exacerbated.
The expansion would be considered impressive in most markets, but it represents an ongoing slowdown for China, the world's second-largest film territory and a continual source of growth for Hollywood for the better part of a decade.

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

课程安排:为期一周的课前培训后,学员在每周末的星期五和星期六交替上课,周五晚提供住宿。最后一个学期需住校学习两周,其余时间在线完成学习任务。
单词turkey 联想记忆:

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

“It comes down to answering these questions: how do you continue to iterate the platform, how do you continue to augment the team, and how do you build a tapestry of alliances with partners that will accelerate your growth?” Case said.
小女孩名叫Neshama Spielman,来自耶路撒冷。她是4年前在“圣殿山筛选项目”中发现这个护符的。该项目旨在检查从神圣犹太教遗址移来,未经考古检测过的泥土。当年,Spielman只有8岁。
单词embrace 联想记忆:

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

3.9 全面加强政府自身建设

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

Google's brand is now worth more than 109 billion U.S. dollars, around 2 billion dollars more than Apple, making it the most lucrative in the world.
事实上,贷款给Seppenwolde的那些机构一个荷兰盾都没损失。他们在几周内就清空了全部的东印度股票,收回了所有贷款。

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

n. 轨道(track的复数);磁道;轮胎
The new numbers, reported by a tracking initiative called the Global Carbon Project and published in the journal Nature Geoscience, came on the eve of a United Nations summit meeting meant to harness fresh political ambition in tackling climate change. Scientists said the figures showed that vastly greater efforts would be needed to get long-term global warming within tolerable limits.

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
From the themed collection: 上半年全国陶瓷出口数据公布
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

While British schools moved up two places on average, French schools, the largest group from any one country, fell one place on average. EMLyon Business School dropped outside the MBA ranking and lost 15 places overall, while Edhec Business School failed to make it into the Executive MBA ranking and lost eight places overall as a result.
Businesswomen are booming in Asia: The whole region makes a strong showing, from China and Singapore to New Zealand and Thailand. Entrepreneurship is on the rise: see Zhang Xin (No. 50) , Sun Yafang (No. 77) and Solina Chau (No. 80). And Asian region women are showing their political might, from newcomer Park Geun-hye, the South Korean president (No. 11) and Burmese dissident and parliamentarian Aung San Suu Kyi (No. 29) to Australian PM Julia Gillard (No. 28) and Thai Prime Minister Yingluck Shinawatra (No. 31).

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

Britain saw a 66 percent increase in its foreign-born population between 2004 and 2014. Voters who chose “leave” in the recent referendum overwhelmingly cited immigration as their main concern.
The unemployment rate has plunged over the past three years to 5.8% from 8.6%, but almost nobody, including the Federal Reserve, thinks the labor market is really that healthy.

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
From the themed collection: 广州大都市区规划将进入编制阶段
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

"I want to tell you what happened I opened the envelope and it said Emma Stone, La La Land and that is why I took such a long look at Faye and at you. I wasn't trying to be funny. This is Moonlight for best picture," Beatty told the shocked crowd as he explained the blunder.

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

该机构在2014年的一项调查显示,在完成两年教学的受访者当中,86%表示他们通过自己的工作为改变教育不平等采取了行动,65%表示在工作以外采取了行动。
以下是人们经常用来描述自己的一些句子。
sen年老+ior表形容词,“较…的”→年长的
5. 格罗斯警告:“庞氏骗局!临界点!信贷超新星!”

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

3. Your boss received your résumé from a contact of a contact。

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

十年前,斯蒂尔作为一名成功的投资顾问在世界电信展(ITU World)上发言。世界电信展是联合国主导的一项活动,重点是科技在政府中的应用。同一周,加州经历了史上第一次州长罢免选举。斯蒂尔不敢相信,在如此重要的选举中,会出现这种不合时宜的平台故障(三年前才刚刚发生了臭名昭著的佛罗里达州总统选举罢免),所以她决定凭一己之力来解决这个问题。到目前为止,共有169个国家使用了Everyone Counts的电子投票平台,包括波斯尼亚黑塞哥利亚和奥斯卡奖评审委员会。
这种现象部分原因可能来自人民币汇率总体的疲软,原因是这会令境外的商品变得更加昂贵。今年1月人民币汇率下跌了1.3%,而在2015年最后一个季度人民币贬值了2.2%。不过,中国的出口仍未因人民币贬值而受到提振。
上周四,中国电影资料馆副馆长张晓光表示,这些电影从来自100个国家的2000多部候选影片中脱颖而出,将于4月8日到23日期间在北京30多个电影院和大学放映。

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

4. Statistician
节目2 歌曲《中国味道》,凤凰传奇

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

美国的实际GDP在7-9月份内比去年同期增长了3.9%,这是官方上个月发布的数据。
adj. 优雅的,精美的,俊美的

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

7、Bad body language habits

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

Consumer prices continued to rebound from an August dip, accelerating 0.2 percentage points to 2.1 per cent year on year, bang-on analysts’ median forecast.
Do not forget why you're attending these conferences, who you're doing this for -- we are your own children. You are deciding what kind of world we will grow up in. Parents should be able to comfort their children by saying "everyting's going to be alright" , "we're doing the best we can" and "it's not the end of the world". 不要忘记你们为何而来到这里开会,你们为谁做事情?我们是你们的下一代,你们正在决定我们将要在一个什么样的环境中成长,父母需要能够宽慰孩子们,告诉他们“一切都没问题,那不是世界末日,我们正在尽其所能的改变”。
“我们非常确信成交价会达到预测的最高价。”

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
From the themed collection: 长租公寓过度金融化值得警惕
Paper

Length-scale dependence of protein hydration-shell density

UK schools account for more than a third of all graduates from the top 50 pre-experience programmes and not only attracted nearly half of all female students but also almost half of all international students. Indeed, 94 per cent of students enrolled in a UK MiF pre-experience programme in 2014 were from overseas. About 85 per cent of these students were from outside the European Economic Area, including 55 per cent of the overall number from mainland China.
But I don't think you can say that to us anymore. Are we even on your list of priorities? My father always says "You are what you do, not what you say." 但我不能再相信这样的话了,孩子们还是你们的优选名单吗?我爸爸总是说:“听其言,观其行,是认识一个人最好的方法”。
中国拥有世界上最大的外汇储备,它一直被视为金融稳定的最终保障,因为外储可以被用来对冲资本外流,或纾困艰难应对坏账增加的国内金融机构。
Be passionate about learning.

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

By the end of 2015, Shanghai's population of migrant residents had decreased to 9.8 million, comprising 40.6 percent of the city's roughly 24 million permanent residents, according to statistics released by the Shanghai Municipal Statistics Bureau on Monday.
1. 仅根据薪水选工作

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

2015年,全球范围发起的233起反倾销案件中,针对金属行业的案件占比达创纪录的46%,几乎全部是针对钢铁行业的案件。
在做完所有他能做的自救措施后,这个务实的孩子不知道还要多久才会有人来救他,于是他决定做家庭作业。
德马库斯-考辛斯、塞尔吉-伊巴卡和路易斯-威廉姆斯的交易早在截止时间——美国东部时间周四下午3点之前就已经完成了,在余下完成压哨交易的角色球员里,只有像泰-吉布森和PJ-塔克算是相对大牌的球员了。

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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We took further steps to implement the Internet Plus action plan and the national big data strategy.
We learned that nothing brings people together like the sun hiding behind the moon.

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